Separácia izomérov metamfetamínu pomocou kyseliny vínnej

[Osmosis Vanderwaal]

@G.Patton S týmto postupom mám niekoľko problémov, ktoré mi, dúfam, dokážete vysvetliť.
Nie je tam žiadna zmienka o D-meth-D-tartáte alebo l-meth-l-tartáte. Ide o opticky aktívne stereoizoméry a nevidel som žiadny dôkaz ani mechanizmus, ktorý by naznačoval, že sa netvoria. Keďže ide o opticky aktívne stereoizoméry, kryštalizovali by pri vyššej teplote (t. j. skôr) ako neaktívne. Poradie by bolo nasledovné: D,D; L,L; D,L; L,D.
Prečo by nebolo nákladovo efektívnejšie a účinnejšie použiť JEN kyselinu l-vínnu, prirodzene sa vyskytujúce izoméry, a pred zahustením a kryštalizáciou odstrániť z rm kryštály ,l l-meth?

 

[G.Patton]

Je to spôsobené priestorovými prekážkami. Tie sa nedajú tvoriť. To je opísané v literatúre s ďalšími príkladmi amínov. Vyhľadajte si ho, ak vás zaujíma.

Môžete, je to na vás. Výsledok bude rovnaký.

 

[EveryoneHatesCris]

Okay?

 

[Osmosis Vanderwaal]

@G.Patton I find it interesting that you are reacting ammonium chloride with sulfuric acid to make your HCL gas in this write up. I've never before heard of using that method but it is viable. Is there a reason that is preffered over the more common mixtures?

 

[G.Patton]

No difference, It's up you your local reagent availability.

 

[Osmosis Vanderwaal]

I like that there is no water to gunk up the works, like there is dehydrating HCL with H2So4. I think I'll adot this method andski the drying tube

 

[G.Patton]

It's easy to get rid of water by means of CaCl2 tube filter.

 

[Osmosis Vanderwaal]

sure, or a cold trap with H2So4 inline with the output, but if I skip that I can just have a flask, a claison adaptor with a pressure equalizing drop funnel and a hose adaptor on the side arm. 4 pieces of glass, only the drop funnel being extra from a basic distillation set

 

[prvnc]

The tartaric acid method works by selectively crystallizing d-methamphetamine as the l-tartrate salt. Control pH carefully during freebase conversion and HCl gas saturation. Hot filtration and recrystallization in ethanol boost purity but reduce yield (~30% loss normal). Always verify purity with Simon’s test. Exact tartaric acid ratios and repeat crystallizations improve results.

 

[Osmosis Vanderwaal]

theres a rule that says "a good chmist is an accurate chemist" Tartaric acid doesn't "selectively crystallise" anything. that misleading Also d-meth-l tartrate mixes more than one convention of chirality, considering
d-meth=L-Meth=R=meth=legal, and
l-meth=D-meth=S-meth=illegal