Mefedrono (4-MMC) sintezė; lengva atlikti - didelė išeiga

[tucoXxX]

Noriu beveik 1 kg galutinio produkto. ar galiu jį pagaminti iš 3 kartus didesnio reagentų kiekio?

 

[olduser]

geriau imti x4 : 2Kg bromoketono, kai kurie žmonės nepasiekia net 50% išeigos + jei norite jo kristalų pavidalo, jūsų išeiga sumažėja

 

[w2x3f5]

nepakanka tirpiklio, 2,5 valandos yra per daug, o temperatūra per aukšta, įpylus rūgšties medžiaga pasirodė labai nešvari.

 

[SonicNL]

Laikotarpis ir laikas yra tinkami. Turbūt padarėte klaidą.

 

[ghostimage]

28-32с, 1h40min, full reaction so i agree with you, i am a bulk manufacturer, make minimum of 15kgs in one turn, so this parameters cost me about a year of experiments, and you here give it to people, who just dont belive you....ahahahah what a lol ;(

 

[HerrHaber]

Neseniai pasiekiau didesnę nei girdėta 4MMC hidrochlorido išeigą tuo metu, kai to mažiausiai tikėjausi. Prieš paskelbdamas tai visiems, manau, kad reikia atlikti daugiau nei 5 bandymus (iš 5 bandymų 2 iš eilės buvo didelės išeigos, tada 2, kuriuos maniau, kad pagerinsiu, bet nepagerinau, o dar vienas sudaro trigubą kopiją, kurios reikia, kad galėčiau tai teigti). Tačiau aš išbėgau iš daiktų ir aš tikiuosi visiškai dokumentuoti tai su nuotraukomis ir visa tai. Ir kad nebūčiau teisiamas už "brangios" informacijos slėpimą, galiu iškeisti kai kurias kontraversiškas pasirengimo detales:

-maišymas yra labai svarbus (kad DCM ir vandens sluoksniai palaikytų kuo glaudesnį kontaktą be fazių pernašos katalizatoriaus)
santykinai ilgas reakcijos laikas (apie 6-8 val., aš darau pertrauką tiesiog sustabdydamas maišymą, manydamas, kad jei sluoksniai atsiskiria, reakcija beveik sustoja)
-nenaudojamas kaitinimas (mano trečiasis ir ketvirtasis bandymai buvo vidutiniai ir mažesni už išeigą, kai buvo naudojamas švelnus kaitinimas)
-mišinio ir reagentų atšaldymas (rūgštinimo etape atšaldytų skysčių išeiga buvo geriausia)
-greitas filtravimas (iš karto po to, kai kietosios medžiagos nusėda, neleiskite, kad nusėstų, nes dalis produkto pateks į tirpalą)

Tikiuosi, kad tai padės, ir pažadu grįžti su išsamia informacija, o kodėl gi ne, patvirtinimas iš kito aktyvaus nario.

 

[mcdonalds]

hello,
i'm not sure why condenser is used in this syntessis.
is correct that is for condense methylamine gas and keep it in the reaction

 

[Naruto]

No

 

[olduser]

yes, but as methylamine is already in excess I guess it's used to reduce the smell

 

[HerrHaber]

yes, but harmful even more so

 

[William D.]

If you use cooling with liquid nitrogen, the reaction mixture in the flask would simply freeze . Therefore, only an excess that is filtered or evaporates into the atmosphere

 

[Ranbir Singh]

How can change mephedrone powder to crystel form please tell me

 

[dnBQByvHb8Zkawbjpx]

Using the process called crystallization: http://bbzzzsvqcrqtki6umym6itiixfhn...n/threads/mephedrone-4mmc-crystallization.72/

 

[agness]

Can I use a Ethyl acetate instead of Dichloromethane?

 

[olduser]

Yes

 

[lucky2222]

hello thank you for info knowledge was wonder on the sop if you had methylamine HCL instead of methylamine 40%aq what step would you use instead to make it a liquid ? thank you again for your time

 

[William D.]

@lucky2222 there is a lot of information on this forum about this. You can use water or alcohol with sodium hydroxide or triethylamine to produce gas. Triethylamine is more convenient in some cases if it is available to you.

 

[Blazey]

nice, i missed out on this chem before the bans in the uk, glad to see its around still, i wanna try it me as I love mdma

 

[lucky2222]

hello was wondering if there away to substitute methylamine 40%aq with methylamine hcl in this sop ?

 

[Rhales]

Sry I don't understand clearly your question. The addition of water is used to dissolve the polar impurities in the solution after the reaction (2B4M, methylamine, etc). You need to let it a few minutes then throw away all of the water, only the oil stays.
You can addapt the protocol to 3mmc aswell, you need to use 2-bromo-3-methylpropiophenone as main reagent and keep the same molar ratio (as they are isomers, you can keep the exact same amounts).

 

[olduser]

Sry I don't understand clearly your question. The addition of water is used to dissolve the polar impurities in the solution after the reaction (2B4M, methylamine, etc). You need to let it a few minutes then throw away all of the water, only the oil stays.
You can addapt the protocol to 3mmc aswell, you need to use 2-bromo-3-methylpropiophenone as main reagent and keep the same molar ratio (as they are isomers, you can keep the exact same amounts).

 

[Rhales]

If it's your first batch, I recommend using protocols that has been written by the forum experts. These are good too but hasn't always been tested and are more about experimentation once you already know the synth. WillD threads about mephedrone are really good

 

[olduser]

If it's your first batch, I recommend using protocols that has been written by the forum experts. These are good too but hasn't always been tested and are more about experimentation once you already know the synth. WillD threads about mephedrone are really good