Ethiopropamine synthesis.

[BlueDex]

Thiophene and Formaldehyde and Hydrochloric Acid can form Thiophene Methyl Chloride. Then, dissolve in Diethyl Ether and add Magnesium Turnings to form Thiophene Methyl Magnesium Chloride. Then, condense Acetaldehyde and Ethylamine in Diethyl Ether and dry with Anhydrous Magnesium Sulfate for Acetaldehyde Ethylimine and do a grignard reaction to get Ethiopropamine.

Thiophene Methyl Chloride.

Thiophene.

Formaldehyde.

Formaldehyde alternate molecule.

Hydrochloric Acid. Hydrogen Chloride.

Chemical reactions yields sign.

Thiophene Methyl Chloride.

Magnesium Turnings.

Diethyl Ether.

Yields.

Thiophene Methyl Magnesium Chloride.

Acetaldehyde.

Ethylamine.

Acetaldehyde Ethylimine.

Diethyl Ether

Grignard Reaction.

Ethiopropamine.

Magnesium Sulfate Anhydrous.

Magnesium Sulfate Hexahydrate.

Magnesium Sulfate Heptahydrate.

 

[BlueDex]

16×9 Blank White Background.

 

[BlueDex]

Thiophene chloromethylation reaction to Thiophene Methyl Chloride.

Forming the Grignard Reagent Thiophene Methyl Magnesium Chloride from Thiophene Methyl Chloride and Magnesium Turnings using Ultrasound.

 

[BlueDex]

Thiophene Methyl Magnesium Chloride grignard reaction on Acetaldehyde Ethylimine in Diethyl Ether using Ultrasound yields Ethiopropamine (EPA).